Associate Director, Clinical Translational Lead

This is a senior role in the Translational Sciences team which functions out of both our UK and USA sites, providing broad translational sciences support to Adaptimmune’s clinical programs, and to the research teams.
Full Time On-Site/Hybrid Clinical Research
Annually: USD 0 - 0
Translational Research Director
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Adaptimmune is a clinical-stage biopharmaceutical company focused on the development and commercialization of novel immunotherapy products for people with cancer. The Company's unique SPEAR (Specific Peptide Enhanced Affinity Receptor) T-cell platform enables the engineering of T-cells to target and destroy cancer across multiple solid tumors.

Our company culture is rooted in trust, inclusion, our capacity to collaborate, and our commitment to being honest and brave in our desire to successfully transform the lives of people with cancer.


This is a senior role in the Translational Sciences team which functions out of both our UK and USA sites, providing broad translational sciences support to Adaptimmune’s clinical programs, and to the research teams. The Translational Sciences team remit is to support exploration of the mechanism of action of Adaptimmune’s cell therapy products, providing a better understanding of the drivers of safety, efficacy and durability, and guiding identification of biomarkers of response and indication selection. The team also provides valuable insights into tumor immune evasion mechanisms, guiding development of next generation products and provides support to pre-clinical research programs.

In this position you will join a highly collaborative team and work in partnership with diverse functional groups within Adaptimmune and external stakeholders to accomplish translational science objectives. The primary responsibility will be to provide inspirational leadership within the clinically facing Translational team, while providing functional expertise and operational support across all our clinical trials. In this role you will act as the translational sciences representative for early and late development clinical teams as required. This will involve implementing translational strategy and analysing, collating, & communicating data to multiple stakeholders. You will also participate in authoring relevant sections pertaining to translational science/ correlative studies in documentation for regulatory submissions to governmental regulatory agencies and will contribute to external publications.


  • Be a leader within the clinically facing translational sciences team to provide scientific expertise in data communication and operational support across internal and external projects.
  • Participate in clinical project teams as the translational sciences representative, taking responsibility for setting and delivering project strategy.
  • Manage, collate, analyse, interpret and communicate high quality translational data to multiple stakeholders in a timely fashion.
  • Follow up on translational learnings across all stakeholders and feed back into research.
  • Provide relevant sections for regulatory documents.
  • Contribute to clinical protocols as the translational sciences expert.
  • Manage or contribute to external partnerships as required.
  • Represent the company at conferences and scientific meetings externally, making presentations and preparing publications.
  • Stay abreast of the literature in immune cell therapy and clinical biomarkers and communicate internally.
  • Develop good scientific relationships with Investigators and clinical site personnel, presenting data and ensuring good communication.
  • Present strategy and data at advisory boards
  • Communicate strategy and progress to senior management at governance meetings.



  • PhD or MD/PhD in immunology, cell therapy for cancer or a related field
  • Experience in clinical translational sciences in the immuno-oncology field
  • 5+ years of relevant experience in clinical research
  • Proven leadership experience
  • Working knowledge and understanding of the collection, handling and processing of tumor specimens, blood and other clinical samples in a biotech/pharmaceutical industry, academic, or CRO environment
  • Experience in adoptive cell therapy for cancer in a biotech or pharma environment is strongly preferred.

At Adaptimmune we embrace diversity and equality of opportunity. We believe that the more inclusive we are, the better our work will be. We welcome applications to join our team from all qualified candidates, regardless of age, colour, disability, marital status, national origin, race, religion, gender, sexual orientation, gender identity, veteran status or other legally protected category. It is our intent that all qualified applicants will receive equal consideration for employment.

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