Associate Scientist, Biology (Pulmonary)
Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates.
Arrowhead’s corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI and San Diego, CA. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need.
The Position
Arrowhead is seeking a highly motivated biologist to join our growing pulmonary team within the Research Department at our Madison site. The successful candidate will be joining a team dedicated to discovering, developing, and translating novel drug targets.
Responsibilities
- Conduct/execute in vitro, ex vivo and/or in vivo studies to facilitate drug discovery and development
- Establish and develop new protocols and assays to support research programs
- Design and perform in vivo and in vitro functional assays by various methods, and in vivo animal procedures
- Data analysis using biostatistics software and delivery accurate data to manager
- Perform critical experiments independently and summarize data report within expected timeline
- Document all experiment data in electronic lab notebook and other data documentations in timely manner
- Read and apply relevant scientific literature to projects to troubleshoot and solve problems
- Maintain a high level of productivity and quality in the lab
- Occasionally present research findings to project teams
- Occasionally work on weekend or non-regular work hours based on assay requirements
Requirements:
- Bachelor of Science in Cell Biology, Molecular Biology, Biochemistry or related field, master’s degree preferred
- 3+ years of experience in cell biology, molecular biology, immunology, pharmacology, or a related field of biology
- Experience in standard cellular and molecular biology techniques (Cell culture, ELISA, Cell-based assays, Immunofluorescence, Western blotting, Microscopy, RNA/DNA isolation, qPCR)
- Excellent record keeping and experience in data analysis, graphing and presentation
- Ability to work independently and to handle multiple projects and meet deadlines
- Be willing to take challenges for novel assay development and delivery data efficiently to support drug development
- Demonstrated innovation, creativity and resilience in problem solving
- Excellent oral and written communication skills
- Self-motivated team player with the ability to thrive in a fast paced, multi-disciplinary, matrixed environment
Preferred:
- Experience in pulmonary, cardiovascular, CNS or metabolic disease
- Experience with small animal handling and preclinical disease model development in the context of drug discovery is a plus
Wisconsin pay range
$50,000—$90,000 USD
Arrowhead provides competitive salaries and an excellent benefit package.
All applicants must have authorization to work in the US for a company.