Research Associate/Associate Scientist, Histology

Full Time On-Site/Hybrid Clinical Research Histology Scientist Apply for this Job Arrowhead Pharmaceuticals, Inc. (Nasdaq: ARWR) is a clinical stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead’s RNAi-based therapeutics leverage this natural pathway of gene silencing.

Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates.

Arrowhead’s corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI and San Diego, CA. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need.

The Position

The Research Associate/Sr. Research Associate is a member of the Histotechnology team in the Toxicology Department. The Histotechnology team supports the Company’s preclinical drug development efforts by designing studies, collecting, preparing and analyzing samples generated by the Company’s animal studies. The candidate works under the direction of the team lead and employs a wide range routine and non-routine histological methods and analyses.

Responsibilities

• Paraffin & Cryosectioning of animal tissues including liver, lung, kidney and adrenal gland, tumor, heart, muscle, gastrointestinal tract, brain at a thickness of 5-7uM
• Routine automated tissue processing, paraffin embedding of various tissues
• Routine automated staining Leica Spectra, and Ventana
• Immunohistochemical and/or immunofluorescence staining.
• Assist in various projects
• Documentation of procedures and results in lab notebook

Requirements:

• A Bachelor in Cell Biology, Molecular Biology, Biochemistry or a related discipline or HT license with 1-2 years of related experience
• Minimum of one year of experience in a histology lab or research lab environment involving histological work
• Highly detailed oriented individual with the ability to follow procedures and multitask
• Ability to successfully process valuable/delicate samples
• Ability to apply theoretical knowledge and practical techniques to the preparation of tissue samples for microscopic examination by the pathologist
• Proficiency with necessary equipment, including microtome, cryostat, automated slide stainers and microscopes
• Knowledge of tissue composition
• Ability to take direction, follow protocols and produce and communicate results

California pay range

$60,000—$100,000 USD

Arrowhead provides competitive salaries and an excellent benefit package.

All applicants must have authorization to work in the US for a company.